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Dharmacon products including siRNAs are now available from MSC.
Pierce, Perbio and MSC would like to introduce a new member of the Perbio Science family, Dharmacon, Inc. Dharmacon is the world’s leading provider of reliable, high quality RNA oligonucleotides, small interfering RNA (siRNA) and related RNA interference (RNAi) products and technologies for use in gene silencing, a powerful and widely used strategy in academic and pharmaceutical research.
Dharmacon’s siGENOME™ and siARRAY siRNA™ reagents are used to silence individual genes, gene families, and entire metabolic pathways. Dharmacon utilizes a patented state-of-the-art algorithm to rationally design its SMARTselection® and SMARTpool® reagents which are then synthesized using an innovative, proprietary 2´-ACE® RNA synthesis chemistry. SMART® Technology reagents exhibit very high levels of potent and specific levels of gene silencing and are useful in a wide variety ofapplications, from basic life science research to drug candidate identification and screening.
The siGENOME siRNA collection offers SMARTpool siRNA reagents (each pool consists of four siRNAs directed against different regions of one gene) as well as individual SMARTselection designed siRNAs guaranteed to silence any human, mouse or rat gene. These SMART Technology reagents are guaranteed to knock down target gene expression at the mRNA level by at least 75% in standard cell culture conditions.
Highlights:
- Ready-to-use gene silencing reagents for any unique human, mouse or rat gene in the NCBI RefSeq database.
- SMARTpool siRNA reagents and individual duplexes deliver guaranteed gene silencing.
- Dharmacon’s validated, proven SMART Technologies ensure potent and specific silencing.
- Move seamlessly between in vitro and in vivo applications.
- Formats, quantities and prices to suit the needs and budgets of laboratories of any size
Dharmacon’s siARRAY siRNA libraries represent collections of SMARTpool products for human targets grouped by pathway or gene ontology. These pre-formatted sets allow investigators to accelerate your gene-silencing research with Dharmacon siARRAY siRNA libraries: ready-to-use, high-throughput screening platforms for analysis of entire pathways and gene families. SiARRAY siRNA libraries are available for purchase as SMARTpool reagents, or as the set of four individual constituent duplexes, or as both the SMARTpool plus the individual duplexes. Once gene silencing has been optimized with the SMARTpool reagent, individual duplexes may be used to further confirm gene-specific silencing and to validate and characterize the target gene. For more information on the SMARTpool Reagents and many other products from Dharmacon, please visit their web site at www.dharmacon.com.
For additional information on RNA Interference, Dharmacon offers The RNAi Technical Reference & Application Guide. This book contains over 100 pages of useful information including method comparisons, experimental design and protocols. This is available FREE for a limited time.
Visit www.Dharmacon.com to avail of this offer
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