Caveolin-1 (2297) Mouse Monoclonal Antibody

Caveolin-1 (CAV-1)  is a cell membrane-associated structural component of flask-shaped plasma membrane invaginations termed caveolae.¹ CAV-1 is expressed at different levels in different tissues, with the highest in adipocytes, endothelial cells, fibroblasts, alveolar type I pneumocytes, and mesothelial cells.^1-2 Anti-Caveolin-1 immunoreactivity is seen in the vast majority of epithelioid mesotheliomas and Ewing sarcoma/PNET, whereas reactivity in lung adenocarcinomas is only occasionally seen and in a weak and focal pattern.^2-3

Specifications

• Reactivity: paraffin
• Visualization: membranous
• Control: mesothelioma, Ewing sarcoma
• Dilution Range: 1:25-1:100*