CLARIOstar® Plus
The new CLARIOstar®Plus is the latest addition from BMG Labtech. It is their most flexible multi-mode plate reader comes equipped with our patented LVF Monochromators™, filters, and spectrometer. Flexibility combined with the best sensitivity of its class, and their newly developed Enhanced Dynamic Range technology, make it the ideal reader for assay development.
Features
- Innovative monochromators for increased sensitivity
- Fully-flexible wavelengths and bandwidths
- Spectral scanning in ABS, FI and LUM
- Largest dynamic range with no manual intervention
- Rapid full-plate autofocus
- Dedicated features for live cell-based assays
- Ultra-fast data sampling (100 measurements/second)
- Dedicated laser for Alpha Technology
Technical Data
Detection Modes | Fluorescence intensity (incl. FRET) Fluorescence polarization AlphaScreen®/AlphaLISA®/AlphaPlexTM Luminescence (flash and glow) – incl. BRET Time-resolved fluorescence TR-FRET UV/vis absorbance spectra | ||||||||||||||||||||
Measurement Modes | Top and bottom reading Endpoint and kinetic Sequential multi-excitation Sequential multi-emission Spectral scanning (fluorescence, luminescence, absorbance) Ratiometric measurements Well scanning | ||||||||||||||||||||
Microplate Formats | 6- to 1536-well plates, user-definable LVis Plate with 16 low volume microspots (2 μL) | ||||||||||||||||||||
Microplate Carrier |
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Light Sources | High energy xenon flash lamp Dedicated laser for AlphaScreen®/AlphaLISA®/AlphaPlexTM | ||||||||||||||||||||
Detectors | Low-noise photomultiplier tube Read-shifted photomultiplier tube CCD spectrometer | ||||||||||||||||||||
Wavelength Selection | Dual Linear Variable Filter (LVF) Monochromators™ Linear Variable Dichroic Mirror Separates ex & em LVF Monochromators Optical filters: Ex and em slides hold 4 filters each LVF Monochromators + optical filters Use one for ex and the other for em UV/Vis absorbance spectrometer: Full spectra or 8 distinct wavelengths in < 1 sec/well | ||||||||||||||||||||
Optical Filters | Excitation and emission slides for 4 filters each | ||||||||||||||||||||
Optical Path Guides | Top and bottom: free-air optical light path guided by motor-driven mirrors and dichroics | ||||||||||||||||||||
Z-Adjustment | Automatic focal height adjustment (0.1 mm resolution) | ||||||||||||||||||||
Spectral Range |
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Sensitivity |
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Read Times |
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Reagent Injection | Up to 2 built-in reagent injectors Individual injection volumes for each well: 3 to 500 µL (optionally up to 2 mL) Variable injection speed up to 420 µL / s Reagent back flushing | ||||||||||||||||||||
Shaking | Linear, orbital, and double-orbital with user-definable time and speed | ||||||||||||||||||||
Integrated Barcode Reader | Up to two integrated barcode readers | ||||||||||||||||||||
Incubation | +3 °C above ambient up to 45 °C or 65 °C The upper heating plate of the incubation chamber operates at 0.5 °C more than the lower plate. This prevents condensation build-up on the lid or sealer. | ||||||||||||||||||||
Software | Multi-user Reader Control and MARS Data Analysis Software included FDA 21 CFR Part 11 compliantIntegrated fluorophore library | ||||||||||||||||||||
Dimensions | Width: 45 cm, depth: 51 cm, height: 40 cm; weight: 32 kg |