CytoFAST Top
Applications
CytoFAST Top have been designed to guarantee the product, personnel and environmental protection and they are primary suitable for applications such as: preparation and handling of cytotoxic drugs, preparation and manipulation of antineoplastic chemotherapeutics, preparation and manipulation of CMR drugs and any other agents likely to cause genetic alterations or synergetic activities with other materials.
Since CytoFAST Top meet also EN 12469 as for Class II Biohazard cabinets, they can be adopted also for a wide range of disciplines in applications such as: Microbiology, Virology, Haematology, Cell culture, Genetics, Handling of hazardous agents to human beings or animals.
Operational Principles
The ambient air is drawn in from the slots at the stainless-steel base of the front opening and it then passes through the H14 HEPA/ULPA filter bank below work surface, from where it is drawn up and blown into the plenum of the re-circulating and exhaust fan.
The “bio-dynamic sealing system” of the negative pressure plenum ensures that all contaminated particles are kept inside the system and are automatically drawn to the plenum or pressure chamber to be captured by the main re-circulating and exhaust H 14 HEPA/ULPA filters.
The fan system assures that no part of the cabinet comes ever under positive contaminated pressure to the laboratory, thus protecting and preserving the environment and operating personnel from exposure to cytotoxic drug, CMR compounds and agents of bio-contamination.
70% of the filtered air is re-circulated (after passing through a H14 HEPA/ULPA filter) in an air cleanliness in Class ISO 3, according to ISO 14644-1 laminar flow pattern downwards into the work chamber and the remaining 30% is exhausted to atmosphere through another H14 HEPA/ULPA filter.
Specifications
External structure in epoxy powder coated cold-rolled steel for excellent corrosion resistance to the attack by aggressive common chemicals. Alternatively special models with external structure made in AISI 304L stainless steel for superior cleanability are also available on demand.
Rear wall in stainless steel AISI 304 L, designed to conform to requirements and pass the “cleanability test” according to EN12469:2000.
Work surface in stainless steel AISI 316L in one piece (or by sections upon request) which are easily removable for carrying out routine cleaning and/or autoclaving sterilization procedures; closed or perforated on request.
Work chamber in single piece AISI 304 stainless steel for the best cleanibility.
Front window: Stratified hinged safety glass to give easy access to large items. It is provided with gas springs to keep it open during maintenance or sanitization operations.
Re-circulating and extractor fans: two centrifugal fans direct driven motor ( main and exhaust ), with protection factor IP-55, controlled by two automatic independent speed-flow rate regulators and microprocessor system to keep constant airflow, showing laminar flow and protection barrier work conditions.
Filtration: H14 HEPA/ULPA filters with an efficiency better than 99,995 % MPPS (EN-1822). Third bank of class H14 HEPA/ULPA filters with easy replace system is positioned beneath work surface built for handling cytotoxic drugs
Operation Condition: Air cleanliness in Class ISO 3 as per ISO:EN 14644-1.
The user-friendly practical keyboard and the rear-lit LCD will continuously display all required data keeping the user constantly informed of the cabinet conditions in operation, and in particular:
- display of laminar airflow velocity and frontal air barrier velocity
- display of inside and outside temperature
- display of residual lifetime of HEPA/ULPA filters, UV Lamp and activated carbon filter (if fitted)
- display of total number of hours of operation
- display of saturation level of HEPA/ULPA filters.
Audio-visual alarms provided for:
- out of range or incorrect laminar airflow velocity and frontal air barrier velocity
- front window opened
- clogging of HEPA/ULPA filters
- end of life-cycle of UV lamp and saturation of activated carbon filter (if fitted)
- blockage in the exhaust duct ( if fitted )
- fan-motor malfunction
- power failure
Lighting: fluorescent tubes in built-in housing, placed outside the contaminated area.
Aluminum front closure panel that ensures the sealing of the cabinet for sterilization/fumigation.
D.O.P.-DEHS inlet port for testing the HEPA/ULPA filters.
UV sterilizing lamp (optional) installed on the aluminum front closure panel complete two switch-off countdown timers, one variable on a 0-3 hours scale (1 minute steps), the other set to 3 fixed hours.
Direct Ducting: As standard supplied with 200 mm diameter collar on the top of the cabinet for optional direct ducting to facility exhaust system
Products in CytoFAST Top range
| SKU | Name | description |
|---|---|---|
| F00015500000 | CytoFAST Top 209 | Width [cm]: 90 Motor-blowers: Double fan Pressure: Negative |
| F00015600000 | CytoFAST Top 212 | Width [cm]: 120 Motor-blowers: Double fan Pressure: Negative |
| F00015700000 | CytoFAST Top 215 | Width [cm]: 150 Motor-blowers: Double fan Pressure: Negative |
| F00015800000 | CytoFAST Top 218 | Width [cm]: 180 Motor-blowers: Double fan Pressure: Negative |
