Human CCL8 (MCP-2) ELISA MAX™ Deluxe 5 Plates

Chemokine (C-C motif) ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP-2), is a protein which in humans is encoded by the CCL8 gene. CCL8 belongs to the CC chemokine family and is up-regulated in inflammed tissues. It binds to several G proteincoupled receptors including CCR1, CCR2, CCR3 and CCR5. It activates and attracts many different immune cells. High levels of CCL8 are associated with tuberculosis (TB) and graft-versus-host disease (GVHD) following hematopoietic stem-cell transplantation (HSCT). Since it recognizes the receptor CCR5, which is a major co-receptor for HIV-1, CCL8 has been investigated for its potential as an inhibitor for HIV infection.

ELISA Development Systems Engineered for Sensitive, Precise and Reliable Serum and Plasma Cytokine Quantitation

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The ELISA Max™ Set Deluxe is specifically engineered for accurate recovery and measurement of analytes in complex fluids, such as serum and plasma (as well as activated cell cultures) without any interference by confounding serum factors, such as heterophilic antibody or rheumathoid factor.