LEGEND MAX™ Mouse IL-34 ELISA Kit with Pre-coated Plates 5 Pre-coated Plates
IL-34 is a homodimeric glycoprotein which contains 241 amino acids. IL-34 is expressed in heart, brain, lung, liver, kidney, thymus, spleen and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage differentiation, proliferation, and survival.
Elevated levels of IL-34 are seen in the plasma of rheumatoid arthritis patients, but can be decreased in response to therapy. IL-34 levels are also increased in the serum of cancer patients and associated with poor prognosis.
Mouse IL-34 shares 71% sequence identity with human IL-34 on the amino acid level.
LEGEND MAX™ Mouse IL-34 ELISA kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody specific for mouse IL-34. This kit is specifically designed for the accurate quantitation of mouse IL-34 from cell culture supernatant, serum, plasma and other biological fluids. This kit is analytically validated with ready-to-use reagents.
- Reactivity
- Mouse
- Application
ELISA
- Sensitivity
- 8.4 ± 1.8 pg/mL
- Standard Range
- 31.3-2,000 pg/mL
- Materials Not Included
- Microplate reader able to measure absorbance at 450 nm
- Adjustable pipettes to measure volumes ranging from 1 µL to 1,000 µL
- Deionized water
- Wash bottle or automated microplate washer
- Log-Log graph paper or software for data analysis
- Tubes to prepare standard dilutions
- Timer
- Plate Shaker
- Polypropylene vials
- Kit Contents
- Anti-Mouse IL-34 Pre-coated 96-well Strip Microplate
- Mouse IL-34 Dectection Antibody
- Mouse IL-34 Standard
- Avidin-HRP D
- Assay Buffer A
- Wash Buffer (20X)
- Substrate Solution F
- Stop Solution
- Plate Sealers
- Gene ID
- 76527View all products for this Gene ID
- UniProt
- View information about IL-34 on UniProt.org
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